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51-53 For example, some studies have shown that there is no effect of selenium on COPD, 54 although other studies reported that selenium had therapeutic benefits
Unlike other antioxidants that work in specific tissues or target particular free radicals, glutathione functions as a comprehensive cellular protection system
The ROS-mediated damage is further enhanced in older individuals since during aging, GSH levels appear to diminish in numerous tissues, thereby placing cells at increased risk of stress-related death (Maher, 2005)
PubMed 21
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Efforts have also been directed at modulating key proteins in the ferroptosis cascade
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